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Multimodal Imaging in Sympathetic Ophthalmia
Authors:Sarakshi Mahajan  Alessandro Invernizzi  Rupesh Agrawal  Jyotirmay Biswas  Narsing A. Rao
Affiliation:1. Advanced Eye Centre, Post Graduate Institute of Medical Education &2. Research, Chandigarh, India;3. Uveitis and Ocular Infectious Diseases Service – Eye Clinic, Department of Biomedical and Clinical Science, “Luigi Sacco” Liuigi Sacco Hospital, University of Milan, Milan, Italy;4. Department of Clinical Sciences and Community Health, University of Milan, Ophthalmological Unit, IRCCS-Cà Granda Foundation – Ospedale Maggiore Policlinico, Milan, Italy;5. National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore;6. Uveitis and Ocular Pathology Department, Sankara Nethralya, Chennai, India;7. USC Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
Abstract:
Purpose: To show the current status of multimodal imaging and its role in supporting an early diagnosis of sympathetic ophthalmia.

Methods: The diagnosis is mainly clinical supported with ancillary investigations; mainly fluorescein angiography and others, including indocyanine angiography optical coherence tomography (OCT), OCT enhanced depth imaging, autofluorescence imaging, and ultrasonography.

Results: Various imaging modalities such as OCT, autofluorescence imaging and angiography are critical in the diagnosis and management of sympathetic ophthalmia. The clinician must make adequate use of such ancillary investigations in the management of the patients.

Conclusions: Sympathetic ophthalmia is a rare, bilateral inflammation of the uveal tract following penetrating trauma or surgery in one eye. The intraocular inflammation requires a prompt diagnosis so that the treatment can be initiated as early as possible.

Keywords:Autofluorescence  fluorescein angiography  indocyanine green angiography  OCT-enhanced depth imaging  sympathetic ophthalmia
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