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Lymphocytic Meningitis in Patients with Sympathetic Ophthalmia |
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| Authors: | Mathilde Goudot Matthieu Groh Sawsen Salah Dominique Monnet Philippe Blanche |
| Affiliation: | 1. Department of Ophthalmology, H?pital Cochin, Assistance Publique H?pitaux de Paris, Université Paris Descartes, Paris, France;2. Department of Internal Medicine, National Referral Center for Rare Autoimmune and Systemic Diseases, H?pital Cochin, Assistance Publique H?pitaux de Paris, Université Paris Descartes, Paris, France |
| Abstract: | Purpose: This study aimed at reporting lymphocytic meningitis in patients diagnosed with sympathetic ophthalmia (SO). Methods: In this single-center retrospective observational case series, we reviewed cases diagnosed with SO. We analyzed the patients’ inciting injuries, the characteristics of uveitis and the cerebrospinal fluid (CSF) analyses. Results: Nine patients were diagnosed with SO and CSF analyses were available in all cases. Four cases had lymphocytic pleocytosis, 3 of which showed marked CSF inflammation with more than 300 lymphocytes/mm3. The inciting event in these 3 patients was a globe perforation injury, whereas 4 patients without meningitis had SO following a surgical intervention. Conclusions: In this case series of patients with SO, lymphocytic meningitis was a common finding. The prevalence of meningitis in patients with SO and its value for the diagnosis of the disease needs to be further studied. |
| Keywords: | Cerebrospinal fluid pleocytosis lumbar puncture meningitis panuveitis sympathetic ophthalmia |