异丙酚复合咪唑安定用于老年患者胃镜检查的临床研究

目的：观察老年患者胃镜检查中使用异丙酚复合咪唑安定的麻醉效果及安全性.方法：40例ASA I～II级,年龄65～80岁,进行胃镜检查的老年患者,随机分为对照组（C组）和麻醉组（A组）,A组静脉注射咪唑安定和异丙酚,意识消失后进行胃镜检查;C组静脉注射生理盐水作为对照.比较两组患者在胃镜检查前、中、后的血压、心率、SpO2的变化,及检查中患者反应、操作时间、检查成功率.结果：A组检查中心率和血压比检查前基础值明显降低,与C组相比亦有显著差异,均未经特殊处理,检查后恢复正常;两组SpO2均无明显变化;A组在患者反应、舒适性、操作时间及检查成功率等方面明显优于C组.结论：胃镜检查应用异丙酚复合咪唑安定可使老年患者镇静、舒适、安全,易于接受.

Propofol anesthesia with midazolam in the elderly patients undergoing gastroscopy

Objective:To observe the effect and safety of propofol anesthesia with midazolam in the elderly patients undergoing gastroscopy.Methods: Forty ASA physical status I-II patients,aged from 65 to 80 years,were(randomly) divided into two groups: control group(C) and anesthesia group(A).Group C was not given anesthesia intravenously during gastroscopy.Group A was intravenously given with propofol and midazolam.During the(gastroscopy),patient's response,proceeding times,satisfaction degree,rate of success,SBP,DBP,HR and SpO_2 were recorded.Results: SBP,DBP and HR decreased significantly after anesthesia in Group A,and were(significantly) lower than those in Group C,but returned to normal gradually after gastroscopy.There was no(remarkable) difference in SpO_2 between the two groups.Compared with Group C,there were fewer side effects,higher satisfaction,shorter proceeding times in Group A.Conclusion: Combined use of propofol and midazolam during gastroscopy is effective,safe and comfortable for the elderly patients.