Extra-and intracellular collagen resorption by smooth muscle cells in postpartum uterine involution |
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Authors: | V. V. Ryvnyak V. S. Gudumak M. A. Rybakova O. F. Grumeza A. V. Pelin |
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Affiliation: | (1) Central Research Laboratory, Department of Histology, N. Testemitsianu State University of Medicine and Pharmacy, Kishinev, Moldova |
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Abstract: | Localization of cathepsin B in rat uterus during postpartum involution is studied using electron histochemical technique. High extracellular activity of cathepsin B and accumulation of products on the cytolemma of smooth muscle cells and adjacent collagen fibrils are revealed. These findings suggest that smooth muscle cells participate in the extracellular collagen degradation via secretion of cathepsin B. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 1, pp. 106–108, January, 1999 |
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Keywords: | postpartum uterine involution collagen resorption smooth muscle cells cathepsin B electron histochemistry |
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