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Extra-and intracellular collagen resorption by smooth muscle cells in postpartum uterine involution
Authors:V. V. Ryvnyak  V. S. Gudumak  M. A. Rybakova  O. F. Grumeza  A. V. Pelin
Affiliation:(1) Central Research Laboratory, Department of Histology, N. Testemitsianu State University of Medicine and Pharmacy, Kishinev, Moldova
Abstract:
Localization of cathepsin B in rat uterus during postpartum involution is studied using electron histochemical technique. High extracellular activity of cathepsin B and accumulation of products on the cytolemma of smooth muscle cells and adjacent collagen fibrils are revealed. These findings suggest that smooth muscle cells participate in the extracellular collagen degradation via secretion of cathepsin B. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 1, pp. 106–108, January, 1999
Keywords:postpartum uterine involution  collagen resorption  smooth muscle cells  cathepsin B  electron histochemistry
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