脑卒中患者焦虑和抑郁性障碍的初步研究

目的研究脑卒中患者焦虑和抑郁性障碍的发生率和治疗效果。方法用汉密尔顿焦虑量表(HAMA)和抑郁量表(HAMD)评估86例脑卒中病人，对伴有焦虑、抑郁性障碍者，用苯二氮萆类、氟西汀、万拉法新治疗。结果86例患者中，焦虑、抑郁性障碍的发生率分别为48.8％、38.4％，治疗好转率分别为83.3％、75.8％。治疗后HAMA和HAMD积分较治疗前明显减少(P＜0.01)。结论焦虑、抑郁性障碍在脑卒中患者中的发生率高，抗焦虑、抑郁治疗的疗效显著。

A preliuminary study ofanxious and depressive disorders in patients with stroke

Objective To study the frequencies and therapeutic effect of anxious and depressive disorders in patients with stroke.Methods 86 patients were assessed with Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD).The patients with anxious and depressive disorders were treated with antianxiety agents and antidepressants such as benzodiazepines,fluoxetine,and venlafaxine.Results In the 86 patients,the frequencies of anxious and depressive disorders were 48^8%,38^4%,respectively,recovery rates of treatment were 83^3%,75^8%,respectively,in which the scores of HAMA and HAMD after treatment were much less than that before treatment(P<0^01).Conclusion The frequencies of anxious and depressive disorders in patients with stroke are very high,and the apparent effect of antianxiety agents and antidepressants are observed.