河北省HIV-1感染者中HCV和HBV合并感染状况调查

目的了解河北省艾滋病病毒Ⅰ型(HIV-1)感染者中,丙型肝炎病毒(HCV)、乙型肝炎(乙肝)病毒(HBV)的感染状况。方法采集了HIV-1感染者的抗凝全血样品,进行了HCV抗体和乙肝病毒表面抗原(HBsAg)的检测。结果 147例HIV-1感染者中,HCV感染率为17.7%(26/147),HBV感染率为15.0%(22/147),HCV/HBV混合感染率为3.4%(5/147)。在HIV-1感染者中,HCV的感染率在注射吸毒感染者中为100%(6/6),血液途径感染者中为73.3%(11/15),性感染者中为6.3%(7/111),不同感染途径间的差异有统计学意义(P<0.001);女性高于男性(P=0.002);低文化程度的感染者中感染率较高,文化程度方面差异有统计学意义(P<0.01)。在HIV-1感染者中,HBV的感染率小年龄组较高(P<0.05)。结论在HIV感染人群中,有较高的HCV和HBV感染率。

Study on HCV and HBV co-infection among HIV-1 infected people in Hebei Province

Objective To study the ratios of HCV and HBV co-infection among HIV-1 infected people in Hebei Province.Method Peripheral blood was collected for testing HCV antibody and HBsAg in HIV-1 infected individuals.Results Of the 147 HIV-1 infected individuals receiving blood tests,17.7%(26/147)were infected with HCV,15.0%(22/147) were infected with HBV,and 3.4%(5/147) were co-infected with HCV/HBV.The statistical analysis showed a significant difference in the ratios of HCV co-infection among individuals who were infected with HIV through different routes(P<0.001).The ratios of HCV co-infection were 100.0%(6/6)in injecting drug users.In those infected via blood transmission and sexual behaviors,the ratios of HCV co-infection were 73.3%(11/15) and 6.3%(7/111)respectively.HIV infected females had a higher ratio of HCV co-infection than males(P=0.002).Statistically significant difference was found in ratio of HCV co-infection among individuals with various educational backgrounds(P<0.01).HIV infected individuals with lower education had higher HCV co-infection ratio.Statistically significant difference was also observed in ratio of HCV co-infection among HIV infected individuals of different ages(P<0.05).HIV infected individuals of lower age had higher HBV co-infection ratio.Conclusion There are higher ratios of HCV and HBV co-infection in HIV-1 infected individuals.