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| Notch信号通路在肠黏膜屏障中的研究进展 | |
| 引用本文： | 王娜,董欢. Notch信号通路在肠黏膜屏障中的研究进展[J]. 基础医学与临床, 2019, 39(3): 434-438 |
| 作者姓名： | 王娜 董欢 |
| 作者单位： | 河北医科大学第二医院 消化科 河北省消化病研究所 河北省消化病重点实验室,河北 石家庄,050000;河北医科大学第二医院 消化科 河北省消化病研究所 河北省消化病重点实验室,河北 石家庄,050000 |
| 摘 要： | Notch信号通路是一种介导细胞与细胞之间信号级联反应的高度保守的通路。其对于多种细胞的分化、增值和凋亡具有调节作用。该信号通路的激活或失活在肠黏膜屏障中发挥着非常重要的作用。对指导各种疾病中所引起的肠黏膜屏障损伤的治疗提供新的视野和思路。 |
| 关 键 词： | NOTCH信号通路 肠黏膜 肠黏膜屏障 肠道上皮细胞 |
Research progress of Notch signaling pathway in intestinal mucosal barrier |
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| WANG Na,DONG Huan. Research progress of Notch signaling pathway in intestinal mucosal barrier[J]. Basic Medical Sciences and Clinics, 2019, 39(3): 434-438 | |
| Authors: | WANG Na DONG Huan |
| Affiliation: | (Department of Gastroenterology,the Second Hospital of Hebei Medical University,Hebei Key Laboratory of Gastroenterology, Hebei Institute of Gastroenterology,Shijiazhuang 050000,China) |
| Abstract: | Notch signaling pathway is a highly conserved signaling pathway that directly mediates the signal cascade among cells. It has a regulatory effect on differentiation, proliferation, and apoptosis of a variety of cells. It has been found that activation or inactivation of Notch signaling pathway plays a very important role in the intestinal mucosal barrier,and provides new insights and ideas for the treatment of intestinal mucosal barrier damage caused by various diseases. |
| Keywords: | Notch signaling pathway intestinal mucosa intestinal mucosal barrier intestinal epithelial cells |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |