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国产固体碘伏的毒性研究
引用本文:黄杰,雍延平.国产固体碘伏的毒性研究[J].中国消毒学杂志,1991,8(4):226-230.
作者姓名:黄杰  雍延平
作者单位:南京市卫生防疫站,南京市卫生防疫站,南京市卫生防疫站,南京大学化学系,南京大学化学系 南京 210003,南京 210003,南京 210003
摘    要:实验室内测定了国产固体碘伏的急性毒性、蓄积毒性、致突变性以及对皮肤和眼的刺激性,并对该消毒剂的安全性进行了初步评价。

关 键 词:碘伏  毒性  致突变试验

STUDY ON TOXICITY OF CHINA-MADE SOLID IODOPHOR
Huang Jie Gong Xiaozhong Zeng Xi Yong Yanping Huang Mushan.STUDY ON TOXICITY OF CHINA-MADE SOLID IODOPHOR[J].Chinese Journal of Disinfection,1991,8(4):226-230.
Authors:Huang Jie Gong Xiaozhong Zeng Xi Yong Yanping Huang Mushan
Institution:Huang Jie Gong Xiaozhong Zeng Xi Yong Yanping~* Huang Mushan~*
Abstract:The toxicity of the solid iodophor developed by Chemical Department, Nanjing University, was measured in laboratory. It was showed in experiment that the oral LD_(50) of the disinfectant in mice was 2870 mg / kg, and the toxicity was weakly cumulative. No mutagenic reaction was observed in sperm malformation test (57~1435 mg / kg) , micronucleus test (57~1435 mg / kg) and Ames test (0.1~1000μg / dish). No irritative reaction was found in rabbit skin patch test and eye irritation test (5000 ppm). On the basis of the experimental results, it is considered that the China-made solid iodophor is safe for use in disinfection practice.
Keywords:iodophor  toxicity  mutagenic test  
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