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多囊卵巢综合征卵巢源性高雄激素血症发生机制研究进展
引用本文:吴春凤,刘芸. 多囊卵巢综合征卵巢源性高雄激素血症发生机制研究进展[J]. 医疗保健器具, 2011, 18(1): 147-149. DOI: 10.3936/j.issn.1674-4659.2011.01.0147
作者姓名:吴春凤  刘芸
作者单位:1. 福建中医药大学,福建,福州,350108
2. 南京军区福州总医院,生殖医学中心,福建,福州,350025
摘    要:
高雄激素血症是多囊卵巢综合征(PCOS)典型的临床特征。卵巢是女性雄激素的主要来源,卵巢内的雄激素是胆固醇在类固醇激素合成酶的作用下合成的,其酶活性异常可引起雄激素水平的上升。本文对PCOS患者卵巢类固醇激素合成关键酶及促黄体生成素,胰岛素改变所导致的卵巢源性雄激素水平升高的形成机制作一综述。

关 键 词:多囊卵巢综合征  高雄激素血症  卵巢  发生机制

Research Progress on Mechanism of Ovariogenic Hyperandrogenism of Polycystic Ovary Syndrome
WU Chunfeng,LIU Yun. Research Progress on Mechanism of Ovariogenic Hyperandrogenism of Polycystic Ovary Syndrome[J]. Medicine Healthcare Apparatus, 2011, 18(1): 147-149. DOI: 10.3936/j.issn.1674-4659.2011.01.0147
Authors:WU Chunfeng  LIU Yun
Affiliation:WU Chunfeng 1,LIU Yun 2(1Fujian University of Traditional Chinese Medicine,Fuzhou 350108,China,2Center for Reproductive Medicine,Fuzhou General Hospital of Nanjing Command,Fuzhou 350025,China.
Abstract:
Hyperandrogenism is a typical clinical feature of PCOS.Androgen of women comes from ovary,the androgen is composited under function of the steroid hormone enzyme,and the enzyme's abnormality could cause the upgrade of androgen.This article will illuminate the mechanism of the upgrade of ovariogenic androgen by inducing steroid hormone and luteinizing hormone and insulin change.
Keywords:Polycystic ovary syndrome  Hyperandrogenism  Ovary  Mechanism  
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