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A case of antiphospholipid antibody syndrome that manifested in the course of basal cell carcinoma
Authors:Masanori Funauchi  Toshiaki Yamagata  Masafumi Sugiyama  Shin-ya Ikoma  Mika Sakaguchi  Koji Kinoshita  Akira Kawata
Affiliation:(1) Department of Nephrology and Rheumatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama 589-8511, Japan;(2) Department of Dermatology, Kinki University School of Medicine, Osaka, Japan
Abstract:
A case of antiphospholipid antibody syndrome (APS) is presented, which manifested 5 years after onset of basal cell carcinoma (BCC). There were multiple collateral veins due to portal vein thrombosis. Because immunological abnormalities including anti-cardiolipin β2 glycoprotein-I antibody improved after surgical resection of BCC, it is likely that APS had occurred as a paraneoplastic syndrome with BCC. This case suggests that it is necessary to investigate the presence of APS when BCC is complicated by some coagulopathies.
Keywords:Antiphospholipid antibody syndrome (APS)  Basal cell carcinoma (BCC)  Paraneoplastic  Portal  Thromboembolism
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