| 387例丙型肝炎患者流行病学及临床特征研究 |
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| 引用本文： | 李志勤,武淑环,余祖江,孙长宇,江河清,潘延凤,周言,杨健全,张红宇. 387例丙型肝炎患者流行病学及临床特征研究[J]. 中华医院感染学杂志, 2011, 21(11): 2255-2257 |
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| 作者姓名： | 李志勤 武淑环 余祖江 孙长宇 江河清 潘延凤 周言 杨健全 张红宇 |
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| 作者单位： | 郑州大学第一附属医院感染科,河南郑州,450052 |
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| 摘 要： | 目的了解丙型肝炎患者的流行病学及临床特点。方法对387例确诊为丙型肝炎患者的临床资料采用回顾性的方法进行分析,研究该组人群感染HCV的传播途径、临床表现、病毒学特征。结果 387例患者中263例有输血及血制品应用史,占67.96%,32例有手术史,占8.27%,有偿献血者30例,占7.75%,有拔牙、洗牙、补牙史者15例,占3.88%;387例患者中,318例无明显症状和体征,占82.17%,209例肝功能正常,占54.01%,对291例患者的HCV RNA载量分级统计,以（5×104）5×105拷贝/ml所占百分比最大,占42.61%,其中76例患者进行基因分型,1b型60例,占78.95%,2a型15例,占19.74%。结论丙型肝炎患者感染HCV多经输血及应用血制品途径,此外,洗牙、拔牙、补牙及纹眉、纹眼线、穿耳孔等亦可能是丙型肝炎感染途径;丙型肝炎患者大多无明显症状和体征,肝功能正常,病情隐匿;HCV常见的基因型以1b型为主,2a型其次。
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| 关 键 词： | 丙型肝炎 流行病学 临床特点 |
Epidemiology and clinical features of 387 cases of patients with hepatitis C |
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| LI Zhi-qin,WU Shu-huan,YU Zu-jiang,SUN Chang-yu,JIANG He-qing,PAN Yan-feng,ZHOU Yan,YANG Jian-quan,ZHANG Hong-yu. Epidemiology and clinical features of 387 cases of patients with hepatitis C[J]. Chinese Journal of Nosocomiology, 2011, 21(11): 2255-2257 |
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| Authors: | LI Zhi-qin WU Shu-huan YU Zu-jiang SUN Chang-yu JIANG He-qing PAN Yan-feng ZHOU Yan YANG Jian-quan ZHANG Hong-yu |
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| Affiliation: | LI Zhi-qin,WU Shu-huan,YU Zu-jiang,SUN Chang-yu,JIANG He-qing,PAN Yan-feng,ZHOU Yan,YANG Jian-quan,ZHANG Hong-yu(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,Henan 450052,China) |
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| Abstract: | OBJECTIVE To investigate the epidemiological and clinical features of patients with hepatitis C.METHODS Three hundred and eighty-seven patients with hepatitis C were retrospectively analyzed for their transmission route,clinical manifestations and virological features.RESULTS Among the 387 patients,295 cases(76.23%) had history of blood or blood products transfusion,30 cases(7.75%) had history of donate blood with compensation,15 cases(3.88%)had history of dentistry treatment,7 cases(1.81%) had history of c... |
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| Keywords: | Hepatitis C Epidemiology Clinical features |
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