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大黄素抗胆囊癌作用的研究进展
引用本文:王瑞涛,尹涵,董顺斌,袁伟,柳言平,刘昌. 大黄素抗胆囊癌作用的研究进展[J]. 中国中药杂志, 2014, 39(11): 1976-1978
作者姓名:王瑞涛  尹涵  董顺斌  袁伟  柳言平  刘昌
作者单位:西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061;西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061;西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061;西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061;西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061;西安交通大学 医学院 第一附属医院 肝胆外科, 陕西 西安 710061
摘    要:
大黄素是一种从中草药中提取的有效活性成分,具有抗微生物、抗炎、抗氧化及清除氧自由基、抑制血小板聚集、改善微循环、保护多种器官组织以及广泛的抗肿瘤作用。原发性胆囊癌是胆道系统常见的恶性肿瘤,手术根治性切除率低,缺乏有效的辅助治疗措施。大黄素的广谱抗肿瘤效应已经得到证实,其在胆囊癌的治疗上是否具有确切疗效尚无可靠的临床试验,其抗胆囊癌作用有待进一步实验考证。该文就大黄素抗胆囊癌作用的相关研究进展做一综述。

关 键 词:大黄素  胆囊癌  抗肿瘤  综述
收稿时间:2013-12-08

Research progress of emodin anti-gallbladder carcinoma
WANG Rui-tao,YIN Han,DONG Shun-bin,YUAN Wei,LIU Yan-ping and LIU Chang. Research progress of emodin anti-gallbladder carcinoma[J]. China Journal of Chinese Materia Medica, 2014, 39(11): 1976-1978
Authors:WANG Rui-tao  YIN Han  DONG Shun-bin  YUAN Wei  LIU Yan-ping  LIU Chang
Affiliation:Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China;Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medicine College of Xi'an Jiaotong University, Xi'an 710061, China
Abstract:
Emodin is an effective active ingredient extracted from Chinese herbal medicine, which has the function of antimicrobial, anti-inflammatory, antioxidant and scavenging oxygen free radicals, inhibiting platelet aggregation, improving microcirculation, protecting various organs and tissues as well as a wide range of anti-tumor effect. Primary biliary gallbladder is a common malignant tumor resection rate and lack of effective adjuvant treatment. It has been confirmed that emodin has broad spectrum antitumor effect,whereas, whether it has curative effect in the treatment of gallbladder carcinoma there is no reliable clinical trials confirmed that its resistance to gallbladder carcinoma function needs further experimental research.In this review, we report the research progress of emodin anti-gallbladder carcinoma.
Keywords:emodin  gallbladder carcinoma  antitumor  review
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