Syphilis in Pregnancy |
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| Affiliation: | 1. Hospital Pharmacy Service, Hospital General de Granollers, Av. Francesc Ribas S/n, 08400, Granollers, Barcelona, Spain;2. Intern Medicine Department, Hospital General de Granollers, Av. Francesc Ribas S/n, 08400, Granollers, Barcelona, Spain;3. Intern Medicine Department, Hospital Clinic, C/Villarroel 170, 08036, Barcelona, Barcelona, Spain;4. Hospital Pharmacy Service, Fundación Privada Hospital d''Olot i Comarcal de la Garrotxa, Avinguda Dels Països Catalans, 86, 17800, Olot, Girona, Spain;5. Clinical Pharmacy and Pharmacotherapy Unit, UB Faculty of Pharmacy, Av. Joan XXIII, 08028, Barcelona, Barcelona, Spain;1. Department of Molecular Biology and Endocrinology, VINČA Institute of Nuclear Sciences, University of Belgrade, Mike Petrovića Alasa 12-14, 11001 Belgrade, Serbia;2. Département de microbiologie-infectiologie et d’immunologie, Faculté de Médecine, Université Laval, Québec G1V 0A6, QC, Canada;3. Centre de recherche du CHU de Québec – Université Laval, G1V 4G2 QC, Canada;4. Institute for Physiology and Biochemistry, Faculty of Biology, University of Belgrade, Studentski trg 3, 11000 Belgrade, Serbia |
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| Abstract: | Syphilis is a chronic infectious process caused by the spirochete Treponema pallidum. In the pregnant woman, syphilis is generally quite easily treated. Long term effects for the mother are rare. Infection during pregnancy may result in spontaneous abortion, stillbirth or premature delivery. The most devastating manifestations are seen in infants born with congenital syphilis. In the HIV-infected pregnant woman who also is infected with syphilis, treatment with the standard regimes may be inadequate. The recent increase in syphilis among women in their childbearing years requires physicians to reacquaint themselves with this disease. The risk factors, manifestations of syphilis, interpretation of serological tests, and management guidelines for the exposed mother are presented. |
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| Keywords: | Syphilis pregnancy risk factors screening management HIV |
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