| 尿液外泌体作为泌尿系统肿瘤分子标志物的研究进展 |
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| 引用本文： | 许亚龙,陈希,吉进,王富博. 尿液外泌体作为泌尿系统肿瘤分子标志物的研究进展[J]. 中华泌尿外科杂志, 2020, 0(1): 72-75 |
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| 作者姓名： | 许亚龙 陈希 吉进 王富博 |
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| 作者单位： | 上海长海医院泌尿外科 |
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| 基金项目： | 国家自然科学基金(81430058)。 |
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| 摘 要： | 外泌体是由包括肿瘤细胞在内的多种细胞分泌的膜性小囊泡,性状稳定,可反映来源细胞的生理/病理状态,是肿瘤早期诊断和判断预后的分子标志物的良好来源。尿液外泌体直接来源于泌尿系统,对泌尿系统肿瘤的诊断和判断预后有更加直接的作用。本文对尿液外泌体作为泌尿系统肿瘤早期诊断分子标志物的研究进展进行综述。
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| 关 键 词： | 尿 外泌体 泌尿系统肿瘤 分子标志物 诊断 预后 |
Advances in the study of urinary exosomes as biomarkers of genitourinary tumors |
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| Xu Yalong,Chen Xi,Ji Jin,Wang Fubo. Advances in the study of urinary exosomes as biomarkers of genitourinary tumors[J]. Chinese Journal of Urology, 2020, 0(1): 72-75 |
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| Authors: | Xu Yalong Chen Xi Ji Jin Wang Fubo |
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| Affiliation: | (Department of Urology,Shanghai Changhai Hosipital,Shanghai 200433,China) |
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| Abstract: | Exosomes are membranous vesicles secreted by a variety of cells,including tumor cells,with stable characters,which can reflect the physiological/pathological state of the source cells,indicating good sources of biomarkers for early diagnosis and prognosis of tumors.Urine exosomes are directly derived from the urinary system and play a more direct role in the diagnosis and prognosis of urinary system tumors.This paper reviews the recent advances in urinary exosomes as molecular markers for the early diagnosis of genitourinary tumors. |
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| Keywords: | Urine Exosome Genitourinary tumors Biomarkers Diagnosis Prognosis |
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