延续性护理在造血干细胞移植术后患者中应用效果的三年随访研究

目的分析、探讨延续护理对恶性血液病行造血干细胞移植术后出院患者生活质量及心境状态的影响。方法选择2012年1月-2015年10月在我院血液科行造血干细胞移植术的恶性血液病患者共120例,采用随机数字表法分为对照组58例和干预组62例。两组患者出院时均按护理常规给予出院指导,干预组患者出院后按延续护理方案给予干预。在实施干预前、干预6个月后、干预12个月、干预3年后采用欧洲癌症研究机构治疗组织制定的生活质量量表(QLQ-C30)中文版、造血干细胞移植特异性量表(FACT-BMT量表)和简明心境状态量表(POMS-SF)对患者进行了问卷调查。结果经重复测量方差分析,两组患者生活质量QLQ-C30量表的角色功能、情绪功能、总体健康维度得分,生活质量FACT-BMT量表的情绪稳定状况、功能健康状况、移植特异模块和生活质量总分,心境状况POMS-SF量表得分的紧张、愤怒、精力和抑郁得分的分组效应、时间效应及交互效应差异均有统计学意义(P<0.05)。结论对恶性血液病行造血干细胞移植术后出院患者给予延续护理干预能够有效提高其生活质量,减轻负性情绪。

Three-year follow-up study on the effect of continuous nursing in patients after hematopoietic stem cell transplantation

Objective To analyze and explore the effect of continuous nursing on quality of life and mood of discharged patients with malignant hematological diseases after hematopoietic stem cell transplantation.Methods 120 patients with malignant hematological diseases who underwent hematopoietic stem cell transplantation in our hospital from January 2012 to october 2015 were divided into control group(58 cases)and experimental group(62 cases)by random number table method.Two groups of patients were discharged according to the nursing routine to give discharge guidance,the experimental group was discharged according to the continuation of nursing program to give intervention.Before intervention,6 months after intervention,12 months after intervention and 3 years after intervention,the patients were investigated with QLQ-C30,FACT-BMT and POMS-SF.Results After repeated measurement of variance analysis,the role function,emotional function and overall health dimension scores of QLQ-C30 scale,emotional stability status,functional health status,transplantation specific module and total quality of life scores of FACT-BMT scale,and the tension,anger,energy and depression scores of POMS-SF scale of mood status in the two groups were analyzed,there were significant differences in group effect,time effect and interaction effect(P<0.05).Conclusion Continuous nursing intervention for discharged patients with malignant hematological diseases after hematopoietic stem cell transplantation can effectively improve their quality of life and reduce negative emotions.