针灸对实验性家兔神经损伤尿潴留的影响

目的 :探讨针灸对宫颈癌术后所致尿潴留的作用机理。方法 :选取 3 6只健康雌性家兔 ,针灸“次”、“肾俞”、“三阴交” ,观察对膀胱内压、排尿阈值、残余尿量以及膀胱盆神经放电的影响。结果 :针灸可使上述指标发生逆转 ,治疗组与造模组、对照组对比有显著性差异 (P <0 0 1)。结论 :针灸“次”、“肾俞”、“三阴交”具有治疗宫颈癌术后所致尿潴留的作用 ,其机理可能与针灸对损伤神经的恢复有关。

Influence of Acu-moxibustion on Nerve Injury Induced Urine Retention in the Rabbit

Objective: To observe the effect of acu-moxibustion on urosch esis for studying the mechanism of acu-moxibustion in the treatment of cervical cancer caused retent ion of urine. Methods: Thirty-six rabbits were randomized into c ontrol, model and acu-moxibustion groups, with 12 cases in each group. Uroschesis model was esta b lished by sectioning the rabbit's uterus and the attached nerves. In acu-moxib ustion group, bilateral " Ciliao"(BL 32), "Shenshu"(BL 23) and "Sanyinjiao"(SP 6) were punctured, sti mulated electrically (for 15 min) and also given with moxibustion (for 15 min). Intravesical pressure, micturition threshold, residual urine volume and pelvic nerve discharg e were recorded. Results: Compared with control group, the int ravesical pressure of model group and acu-moxibustion group lowered significant ly ( P <0.01, 0.05), while comparison between the later two groups showed that t he intravesical pressure of acu-moxibustion group was markedly higher than that o f model group, suggesting that acu-moxibustion could raise intravesical pressur e. Comparison among the 3 groups displayed that the micturation threshold and resi dual urine volume of model group and acu-moxibustion group were significantly h ig her than those of control group ( P <0.01); while comparison between model and acu-moxibustion groups displayed that values of these two indices of the late r group were all l ower than those of model group ( P <0.05), meaning the increase of bladder con tractility by acu-moxibustion. Correspondingly, uterotomy induced striking dece as e of firing pulses was corrected, with the firing pulses of acu-moxibustion gro up being significantly more than those of model group ( P < 0.01). C onclu sion: Acu-moxibustion could reduce the retention of urine in the rabbit w ith uterotomy.