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上尿路移行细胞癌静脉尿路造影显影欠佳的临床相关因素
引用本文:李辽源,杨明,张海滨,沈周俊,徐文峰,陈勇,刘建华,林哲,吴振权. 上尿路移行细胞癌静脉尿路造影显影欠佳的临床相关因素[J]. 中国现代医学杂志, 2008, 18(20): 3032-3035
作者姓名:李辽源  杨明  张海滨  沈周俊  徐文峰  陈勇  刘建华  林哲  吴振权
作者单位:1. 中山大学佛山市第一人民医院博士后工作站泌尿外科,广东佛山,528000
2. 上海交通大学医学院附属瑞金医院,泌尿外科,上海,200025
摘    要:
目的 探讨上尿路移行细胞癌(transitional cell carcinoma of the upper urinary tract,UUT-TCC)患者行静脉尿路造影(intravenous urography,IVU)时,显影欠佳(poor or nonvisualization of renal collecting system,PNV)的阳性率及其与肿瘤临床病理参数的关系.方法 回顾分析1990年1月~2005年1月因U-UT-TCC行根治性手术患者172例的临床病理资料.统计并比较术前尿脱落细胞学、行IVU时充盈缺损和PNV的阳性率;采用logistic回归分析模型探讨PNV是否和UUT-TCC临床病理参数之间存在相关性.结果 172例患者中,144例(83.7%)有肉眼血尿,12例(7.0%)有镜下血尿;46例(26.7%)尿脱落细胞学阳性,36例(20.9%)显示充盈缺损,105例(61.0%)显影欠佳.PNV和尿脱落细胞学阳性率比较及PNV和充盈缺损阳性率比较,差异均具有显著性(P值分别为0.031,0.001).单变量logistic回归分析表明PNV和肿瘤分期、分级及肿瘤大小显著相关(P值分别为0.028,0.031,0.006);多变量logistic回归分析表明PNV和肿瘤分期及肿瘤大小显著相关,(P值分别为0.042,0.014).结论 在排除泌尿系结石、感粢及畸形等病因后,IVU中如果出现PNV,应当高度怀疑UUT-TCC可能性;而且UUT-TCC患者出现PNV常常预示着肿瘤分期较高和体积较大.

关 键 词:移行细胞癌  上尿路  静脉尿路造影

Relationship between poor or nonvisualization of renal collecting system in IVU and clinicopathologic characteristics of TCC in the upper urinary tract
LI Liao-yuan , YANG Ming , ZHANG Hai-bin , SHEN Zhou-jun , XU Wen-feng , CHEN Yong , LIU Jian-hua , LIN Zhe , WU Zhen-quan. Relationship between poor or nonvisualization of renal collecting system in IVU and clinicopathologic characteristics of TCC in the upper urinary tract[J]. China Journal of Modern Medicine, 2008, 18(20): 3032-3035
Authors:LI Liao-yuan    YANG Ming    ZHANG Hai-bin    SHEN Zhou-jun    XU Wen-feng    CHEN Yong    LIU Jian-hua    LIN Zhe    WU Zhen-quan
Affiliation:LI Liao-yuan1,YANG Ming1,ZHANG Hai-bin1,SHEN Zhou-jun2,XU Wen-feng1,CHEN Yong1,LIU Jian-hua1,LIN Zhe1,WU Zhen-quan1(1.Department of Urology,Foshan Hospital,Sun Yat-Sen University,Foshan,Guangdong 528000,P.R.China,2.Department of Urology,Ruijin Hospital,Medical College of Shanghai Jiaotong University,Shanghai 200025,P.R.China)
Abstract:
Objective To investigate the positive rate of poor or nonvisualization(PNV) in intravenous urography in patients with transitional cell carcinoma of the upper urinary tract(UUT-TCC) and its correlations with pathological findings and clinical characteristics.MethodsBetween January 1990 and January 2005, a total of 172 consecutive patients with UUT-TCC underwent radical nephroureterectomy in our departments were analyzed retrospectively.Statistical analysis concerning the detection rate of UUT-TCC by preoper...
Keywords:transitional cell carcinoma  upper urinary tract  intravenous urography  
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