通癃胶囊治疗前列腺增生症的临床研究

目的探讨通癃胶囊治疗良性前列腺增生症(BPH)的疗效与安全性。方法90例BPH患者随机分为治疗组60例与对照组30例,治疗组口服通癃胶囊,对照组服用前列康,治疗90 d后评定疗效。结果治疗组降低患者的IPSS评分、提高最大尿流率、减少膀胱残余尿量与对照组比较有显著性差异(P<0.01);缩小患者的前列腺体积与对照组比较有显著性差异(P<0.05)。治疗组治疗前后的性激素测定结果表明:腺体缩小组中,E2治疗后下降,E2/T比值下降,与腺体未缩小组比较有显著性差异(P<0.05)。2组治疗期间均无严重不良事件发生。结论口服通癃胶囊治疗BPH疗效显著,无严重不良反应。 

Clinical Study on Treatment of Hyperplasia of Prostate with Tonglong Capsule

OBJECTIVE To investigate into the effect and safety of Tonglong Capsule in the treatment of hyperplasia of prostate.METHOD 90 patients were randomly divided into a treatment group of 60 patients and a control group of 30 patients,who took Tonglong Capsule and Qianliekang tablet respectively for 90 days.RESULT Marked differences were found between the two groups in IPSS decrease rating,maximum urine flow increase and residual urine volume decrease(P<0.01),and also in prostate volume reduction(P<0.05).The result of sex hormone determination indicated that in the group with prostate volume reduction,E_2 and E_2/T ratio decreased,with marked difference as compared with the group without prostate volume reduction(P<0.05).No serious undesirable accident occurred in both group.CONCLUSION Tonglong Capsule is very effective for hyperplasia of prostate,with no serious side effect.