An antifungal constituent from the stem bark of Butea monosperma |
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| Authors: | B M Bandara N S Kumar K M Samaranayake |
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| Affiliation: | Department of Chemistry, University of Peradeniya, Sri Lanka. |
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| Abstract: | ![]()
The petroleum and ethyl acetate extracts of the stem bark from Butea monosperma displayed antifungal activity against Cladosporium cladosporioides. The active constituent of low polarity was isolated by bioassay-monitored chromatographic fractionation, and identified as (-)-medicarpin by comparison of physical data. The antifungal activity of (-)-medicarpin was found to be greater than that of Benlate, a standard fungicide, while (-)-medicarpin acetate also exhibited significant activity against C. cladosporiodes. |
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