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急诊脓毒症预防中的早期目标导向治疗
引用本文:王仲,柴彦,郭喆,方奕鹏,张会娟. 急诊脓毒症预防中的早期目标导向治疗[J]. 实用休克杂志(中英文), 2020, 0(1): 6-7,13
作者姓名:王仲  柴彦  郭喆  方奕鹏  张会娟
作者单位:清华大学附属北京清华长庚医院;清华大学临床医学院
摘    要:
脓毒症是临床上常见的急危重症,其防治主要是保护脏器功能。糖萼是内皮细胞表面多糖-蛋白复合结构,具有保护细胞屏障、维持器官灌注的功能。在早期监测感染病人血清中糖萼破坏情况,并予以保护,或可保护病人脏器功能,预防感染病人进展为脓毒症,从源头降低脓毒症发病率。本文就糖萼保护与预防脓毒症进展展开综述,为临床上诊疗提供参考。

关 键 词:脓毒症  预防  糖萼  内皮细胞屏障

Early goal-directed therapy in emergency sepsis prevention
Wang Zhong,Chai Yan,Guo Zhe,Fang Yipeng,Zhang Huijuan. Early goal-directed therapy in emergency sepsis prevention[J]. Journal of practical shock, 2020, 0(1): 6-7,13
Authors:Wang Zhong  Chai Yan  Guo Zhe  Fang Yipeng  Zhang Huijuan
Affiliation:(Tsinghua University Affiliated Beijing Tsinghua Changgung Hospital,Beijing,China;School of Clinical Medicine,Tsinghua University,Beijing,China)
Abstract:
Sepsis is a common acute and severe disease in hospital,whose prevention and treatment is major in protecting organs.Glycocalyx is polysaccharide-protein composite structure on the endothelial cell surface,which can protect cell barrier and maintain the function of organic perfusion.So we can monitor glycocalyx destruction and give the corresponding protection in the early infection patients to protect organic function.These measuresm may prevent infectious patients progress to sepsis from the source and reduce the incidence of sepsis.This article reviews the progress in the protection of glycocalyx and prevention of sepsis to provides references for clinical diagnosis and treatment.
Keywords:Sepsis  Prevention  Glycocalyx  Endothelial barrier
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