首页 | 本学科首页   官方微博 | 高级检索  
     


Adenosine-to-inosine editing of endogenous Z-form RNA by the deaminase ADAR1 prevents spontaneous MAVS-dependent type I interferon responses
Affiliation:1. Medical Research Council Human Immunology Unit, Medical Research Council Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 9DS, UK;2. Bioinformatics and Biostatistics STP, The Francis Crick Institute, London, NW1 1AT, UK;3. Centre for Translational Immunology, Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, OX3 7FZ, UK;4. Retroviral Immunology, The Francis Crick Institute, London, NW 1AT, UK;5. Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, W2 1NY, UK
Abstract:
><ol class=
  • Download : Download high-res image (127KB)
  • Download : Download full-size image
  • Keywords:ADAR1  Zα domain  Z-RNA  MDA5  MAVS  interferon  influenza A virus  RNA editing  Aicardi–Goutières syndrome  neutrophil
    本文献已被 ScienceDirect 等数据库收录!
    设为首页 | 免责声明 | 关于勤云 | 加入收藏

    Copyright©北京勤云科技发展有限公司  京ICP备09084417号