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Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: A case report
引用本文:Nakajima Y,Takagi H,Sohara N,Sato K,Kakizaki S,Nomoto K,Suzuki H,Suehiro T,Shimura T,Asao T,Kuwano H,Mori M,Nishikura K. Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: A case report[J]. World journal of gastroenterology : WJG, 2006, 12(11): 1805-1809. DOI: 10.3748/wjg.v12.i11.1805
作者姓名:Nakajima Y  Takagi H  Sohara N  Sato K  Kakizaki S  Nomoto K  Suzuki H  Suehiro T  Shimura T  Asao T  Kuwano H  Mori M  Nishikura K
作者单位:Department of Medicine and Molecular Science Gunma University Graduate School of Medicine Maebashi,Gunma 371-8511,Japan,Department of Medicine and Molecular Science Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Medicine and Molecular Science Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Medicine and Molecular Science Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Medicine and Molecular Science Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Surgery Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Department of Medicine and Molecular Science Gunma University Graduate School of Medicine,Maebashi,Gunma 371-8511,Japan,Division of Molecular and Functional Pathology Department of Cellular Function,Niigata University Graduate School of Medicine and Dental Sciences,Niigata,Niigata 951-8510,Japan
摘    要:
A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasono-graphy. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endo-scopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The resected margin of the tumor was positive for malignant cells. Two courses to transcatheter arterial chemotherapy for liver metastasis were ineffective. Accordingly, the rectal tumor and metastatic lymph nodes were surgically resected. One month after the operation, she received liver transplantation (left lateral segment and caudate lobe) from her son. No recurrent lesion has been observed at two years after the liver transplantation. Liver transplantation should be considered as a treatment option even in advanced case of carcinoid metastasis to the liver. We also discuss the literature on liver transplantation for metastatic carcinoid tumor.

关 键 词:肝移植  肝位移  直肠癌  病理
收稿时间:2005-05-11

Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: a case report
Nakajima Yoshimi,Takagi Hitoshi,Sohara Naondo,Sato Ken,Kakizaki Satoru,Nomoto Kenichi,Suzuki Hideki,Suehiro Taketoshi,Shimura Tatsuo,Asao Takayuki,Kuwano Hiroyuki,Mori Masatomo,Nishikura Ken. Living-related liver transplantation for multiple liver metastases from rectal carcinoid tumor: a case report[J]. World journal of gastroenterology : WJG, 2006, 12(11): 1805-1809. DOI: 10.3748/wjg.v12.i11.1805
Authors:Nakajima Yoshimi  Takagi Hitoshi  Sohara Naondo  Sato Ken  Kakizaki Satoru  Nomoto Kenichi  Suzuki Hideki  Suehiro Taketoshi  Shimura Tatsuo  Asao Takayuki  Kuwano Hiroyuki  Mori Masatomo  Nishikura Ken
Affiliation:1. Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan
2. Department of Surgery, Gunma University Graduate School of Medicine,Maebashi, Gunma 371-8511, Japan
3. Division of Molecular and Functional Pathology,Department of Cellular Function, Niigata University Graduate School of Medicine and Dental Sciences, Niigata, Niigata 951-8510, Japan
Abstract:
A 42-year-old woman was admitted to our hospital because of multiple liver tumors detected by ultrasono-graphy. Colonoscopy revealed submucosal tumor in the rectum, which was considered the primary lesion. Endo-scopic mucosal resection followed by histopathological examination revealed that the tumor was carcinoid. The resected margin of the tumor was positive for malignant cells. Two courses to transcatheter arterial chemotherapy for liver metastasis were ineffective. Accordingly, the rectal tumor and metastatic lymph nodes were surgically resected. One month after the operation, she received liver transplantation (left lateral segment and caudate lobe) from her son. No recurrent lesion has been observed at two years after the liver transplantation. Liver transplantation should be considered as a treatment option even in advanced case of carcinoid metastasis to the liver. We also discuss the literature on liver transplantation for metastatic carcinoid tumor.
Keywords:Carcinoid  Liver metastasis  Living related liver transplantation
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