| 加味当归补血汤对阿霉素肾病大鼠治疗作用的实验研究 |
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| 引用本文： | 魏明刚,张玲,邵家德,陈爱平,高坤,周栋,孙美娟,孙伟,熊佩华.加味当归补血汤对阿霉素肾病大鼠治疗作用的实验研究[J].中华中医药杂志,2011(5):1211-1216. |
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| 作者姓名： | 魏明刚 张玲 邵家德 陈爱平 高坤 周栋 孙美娟 孙伟 熊佩华 |
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| 作者单位： | 苏州大学附属第一医院中西医结合科;江苏省中医院肾科 |
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| 基金项目： | 苏州市科学技术局应用基础研究计划(No.SYS201016);苏州大学青年教师自然科学基金(NO.Q3122937),苏州大学重点学科、“211工程”建设项目(No.14317336)~~ |
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| 摘 要： | 结合肾脏病病机特点及多年临床经验总结出健脾益肾、活血养阴治疗原则指导下应用加味当归补血汤进行阿霉素肾病大鼠实验研究,了解加味当归补血汤对阿霉素肾病大鼠治疗机制、作用靶点及疗效,应用分子生物学方法验证中医药对肾脏病治疗的确切疗效。
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| 关 键 词： | 慢性肾脏病 病机 中医药疗法 实验研究 |
Analysis of basic pathogenesis of chronic renal disease and experimental study of Jiawei Danggui Buxue Tang on adriamycin renal disease rats |
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| Institution: | WEI Ming-gang1,ZHANG Ling1,SHAO Jia-de2,CHEN Ai-ping1,GAO Kun2,ZHOU Dong2,SUN Mei-juan2(SUN Wei2,XIONG Pei-hua1) (1Department of Integrated Chinese and Western Medicine,the First Affiliated Hospital of Soochow University,Soochow 215006,China;2Department of Nephrology,TCM Hospital of Jiangsu Province,Nanjing 210029,China) |
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| Abstract: | The chronic renal disease(CKD)can seriously damage the health of people.More and more people had been diagnosed CKD every year in the world.The traditional Chinese medicine TCM has the special treatment to cure CKD.CKD is one of complicated disease which not only including asthenia and sthenia,but also including blood stasis and humid heat.With the time passing,CKD will be the syndrome of deficiency of qi or the syndrome of yin asthenia.So we can get a better effect by treating the syndrome of deficiency of qi or the syndrome of yin asthenia.At the same time,we must pay attention to heal the syndrome of blood stasis and humid heat which could affect the prognosis of CKD.We analyze the mechanism of the chronic renal disease and use the formulae of Jiawei Danggui Buxue Decoction at experimental study to explcit the effect target by the way of molecular biology. |
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| Keywords: | Chronic renal disease Pathogenesis Traditional Chinese medicine treatment Experimental study |
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