基于冠心病心绞痛患者报告的临床结局评价量表的科学性考评

目的:评价基于冠心病心绞痛患者报告的临床结局评价量表的信度、效度和反应度。方法:多中心收集了237例经冠脉造影证实的患者(159例冠心病心绞痛患者,78例冠状动脉硬化症患者),采用Cronbach’sα系数、Guttman Split-half进行信度分析。采用因子分析考核量表的结构效度;采用Spearman秩相关分析考核量表的内容效度和标准效度;采用独立样本t检验分析区分效度;量表的反应度采用配对t检验来评估。结果:①总量表的Cronbach’sα系数为0.813,分半信度为0.707。②通过因子分析,发现累计贡献率达50.08%;除了条目1以外,各个条目与所属领域均有较强的相关性(均P<0.01),各个条目能较好的代表所属领域的主题;除独立性领域外,总量表、生理领域、心理领域、社会关系领域及社会环境领域具有较好的区分效度(P<0.05);基于冠心病心绞痛患者报告的临床结局评价量表与西雅图心绞痛量表(SAQ)总分之间具有较好的相关性(相关系数0.689,P<0.001)。③基于冠心病心绞痛患者报告的临床结局评价量表具有较好的反应度(均P<0.001)。结论:基于冠心病心绞痛患者报告的临床结局评价量表具有较好的信度、效度和反应度,可用于冠心病心绞痛的临床疗效评价。

Scientific evaluation on rating scale based on angina pectoris patients-reported outcomes

Objective:Reliability,validity and responsiveness analysis of rating scale based on angina pectoris patients-reported outcomes.Methods:237 patients with angina pectoris confirmed by coronary angiography were enrolled with multi-center.(Including 159 patients with angina pectoris,78 patients with coronary artery sclerosis).Methods of Cronbach’s a coefficient and Guttman Split-half were used for reliability analysis.Factor analysis was used for assessment the construct validity of scale.The content validity and criteria validity of scale were assessed by Spearman rank correlation analysis.Discriminated validity of scale were assessed by independent samples t test,and responsiveness of scale were assessed by pair samples t test.Results:①The Cronbach,s α coefficient of scale was 0.813,split-half reliability was 0.707.②Total variance explained of scale was 50.08% by factor analysis.Each entry had a strong correlation with their respective field(P<0.01),each entry can be better to represent the theme of their respective field,except the first entry.The total scale,physical field,psychological field,the field of social relations and social environment of the field had good discriminated validity(P<0.05),except the independence of the field.The total of rating scale based on angina pectoris patients-reported outcomes and Seattle Angina Scale had a good correlation(correlation coefficient was 0.689,P<0.001).③The rating scale based on angina pectoris patients-reported outcomes had good responsiveness(P<0.001).Conclusion:The rating scale based on angina pectoris patients-reported outcomes have good reliability,validity and responsiveness.And the the rating scale based on angina pectoris patients-reported outcomes can be used for clinical evaluation.