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血液病患者血清和骨髓液中5种酶的观察
引用本文:杜汝辉,顾坚,王晓英.血液病患者血清和骨髓液中5种酶的观察[J].福建医科大学学报,1993(4).
作者姓名:杜汝辉  顾坚  王晓英
作者单位:浙江诸暨市人民医院 311800
摘    要:对83例血液病患者骨髓液测定丙氨酸转氨酶(AST),天门冬酸转氨酶(ALT),乳酸脱氢酶(LDH),肌酸磷酸激酶(CPK),羟丁酸脱氢酶(HBD)含量,同时测定19例正常人骨髓液作对比。发现慢性粒细胞的白血病患者骨髓液AST,HBD,LDH,CPK明显升高,分别是正常的3~5倍;急性淋巴细胞白血病的AST是正常的3倍。经化疗完全缓解后,水平均下降至接近正常。测定9例各种白血病患者骨髓CPK的同功酶,以CPK-MB为主,而非白血病者则以CPK-MM或CPK-BB为主。上述改变,可作为白血病病情及疗数判断的参考指标。

关 键 词:血液病  血液  骨髓酶水平

Observation of Enzymes Level in Bone Marrow and Serum in Patients with Hematonsis
Du Ruhui,Gu Jian,Wang Xiaoying.Observation of Enzymes Level in Bone Marrow and Serum in Patients with Hematonsis[J].Journal of Fujian Medical University,1993(4).
Authors:Du Ruhui  Gu Jian  Wang Xiaoying
Institution:Du Ruhui,Gu Jian,Wang Xiaoying Department of Medicine,Zhuji People's Hospital,Zhejiang
Abstract:We investigated levels of alanine transaminase (ALT), aspartic acid transaminase (AST), lactic de- hydrogenase (LDH), creatine phosphokinase (CPK), and hydroxybutyric dehydrogenase (HBD) in bone marrow in patients with hematonosis and 19 controls. The levels of AST,HBD and LDH in chronic my- oloid leukemia were 3 to 5 times as high as that in controls. The above-mentioned enzymes decreased to near normality during complete remission stage after chemotherapy. It was also found that creatine phosphokinase isoenzymes in 9 cases of leukemia were mainly CPK-MB,and CPK-MM or CPK-BB in patients with non-leukemia. This result shows that determination of those enzymes might be used as a parameter for leukemia during the course of treatment.
Keywords:hematonoois  blood  enzyme level of bone marrow  
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