脑卒中后抑郁状态患者的临床观察和分析

目的：观察和分析脑卒中后抑郁状态（PSD）的临床特点、发病情况及其相关因素。方法：用选择性5-HT再摄取抑制剂（SS-RI）对196例脑卒中患者治疗6周，应用抑郁自评量表（SDS）及汉密尔顿抑郁（HAMD）量表对196例脑卒中后抑郁患者进行测评。结果：在应用SSRI治疗3周后，患者HAMD总分降低了50．7G，治疗6周后降低了77．04％；抑郁状态改善明显；在整个治疗过程中没有发现严重不良反应。结论：脑卒中后抑郁发病率与脑损伤及社会心理因素密切相关，应得到临床医师的重视。

Clinical Study on Patients with Poststroke Depression

Objective: To study the clinical features and incidence of depression in the wake of poststroke depression. Methods: 196 stroke patients with poststroke depression were treated with SSRI during the period of an over 6 week of routine treatment . Self-rating Depression Scale (SDS) and I larnilton Depression Scale ( H AMD) were used to evaluate the severity of depression. Results; After treated with SSRI for 3 weeks, the total HAMD scores of the patients decreased by 50. 7%. After treated for 6 weeks, the total scores decreased by 77. 04%. The depression symptoms were greatly improved. During the course, there was no severe side reaction. Conclusion; The incidence of poststroke depression is closely bound up with cerebral hemorrhage and psychic factors, so it should be taken seriously by the clinical doctors.