Abdominal zygomycotic thromboangiitis in a patient with AML and t(1;13;14) |
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| Authors: | E Faber D Riegrová M Jarošová J Hubácek P Slezák Z Pikalová P Hamal K Indrák |
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| Institution: | (1) Department of Hematology, University Hospital, I.P. Pavlova 6, CZ-775 20 Olomouc, Czech Republic,;(2) Institute of Pathology, Medical Faculty, University Palacky, Olomouc, Czech Republic,;(3) Institute of Microbiology, Medical Faculty, University Palacky, Olomouc, Czech Republic, |
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| Abstract: | The case report of a 61 year-old man with AML M2 FAB, t(1; 13; 14) and zygomycotic mesenterial thromboangiitis is presented.
Two induction cycles of chemotherapy were administered due to primary drug resistance. They were complicated by pneumonia,
colonic pseudo-obstruction and perforation with peritonitis. The patient died on the 40th day of therapy, 4 days after undergoing
palliative surgery. Zygomycotic thromboangiitis, which very probably contributed to the intestinal perforation, was confirmed
morphologically at necropsy. The novel complex chromosomal translocation t(1; 13; 14) (q31; q32; q24) and the problems connected
with the diagnosis of invasive fungal infections are discussed.
Received: 26 January 1996 / Accepted: 12 June 1996 |
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| Keywords: | Zygomycosis Fungal infections Acute leukemia Chromosomal abnormalities Ogilvie's syndrome |
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