正常成年人膝关节软骨的MR多序列比较研究

目的　探讨正常成年人膝关节软骨的多序列MR表现及厚度 ,比较其优缺点。方法　选取健康成年志愿者 3 0名 ,男 18名 ,女 12名 ,分别计算并比较T1 WI、T2 WI、PDWI、短 -TI反转恢复序列 (STIR)和三维脂肪抑制扰相梯度回波序列 (3D -FS -SPGR)关节软骨同生理盐水、骨髓和肌肉的对比度噪声比 (CNR) ,观察各序列软骨的MR表现、三维重建并测量软骨厚度。结果　 3D -FS -SPGR序列关节软骨同生理盐水、骨髓和肌肉的CNR值均与其他序列有显著性差异 ;T1 WI和PDWI序列关节软骨约 5 0 % (13 5 0 )表现为 3层改变 ,T2 WI和STIR序列则均表现为单层改变 ,3D -FS -SPGR序列软骨分层与软骨厚度有关 ,最多可见 5层改变 ;3D -FS-SPGR序列软骨厚度的测量值较其他序列准确 ,本组正常男性与女性膝关节各部位关节软骨的平均厚度分别为 (2 .63± 0 .69)mm和 (2 .5 2± 0 .62 )mm。结论　SE序列 ,特别是T1 WI软骨的分层改变与其组织学结构有关 ,但 3D -FS -SPGR序列软骨的分层是由“截断伪影”所致。 3D -FS -SPGR序列较其他序列有着明显的优势 ,能使关节软骨显示更加清晰 ,厚度测量更加准确 ,结合三维重建技术能为临床诊断与治疗提供更多的信息

Normal Articular Cartilage of the Adult Knee:Evaluated with Multiple MR Sequences Imaging

Objective To compare with the advantage or shortage of several scan series in imaging of normal articular cartilage in knee.The MR manifestation were observed and thickness of different location of cartilage in knee in different series were calulated.Methods The knees of 30 healthy volunteers were imaged with five different MR imaging sequences including T 1-weighted,proton density-weighted,T 2-weighted FSE,STIR and 3D-FS-SPGR.The value of CNR were determined for cartilage versus a saline fluid phantom,marrow fat,and muscle.The MR 2D and 3D manifestation were observed and thickness of different location of cartilage in knee in different series were calculated.Results The value of CNR of 3D-FS-SPGR for cartilage versus a saline fluid phantom,marrow fat,and muscle were compared with other sequences and were significantly different.The values of cartilage thickness with 3D-FS-SPGR were more than those with other series.The mulplaner appearance was observed.There was five-plane manifestation when cartilage thickness was more than 4 mm.The value of cartilage thickness of male and female were 2.63 mm and 2.52 mm,respectively.Conclusion 3D-FS-SPGR sequences have significant advantage compared with other series in imaging normal articular cartilage of knee.The cartilage is show clearly than other sequences.The value of cartilage thickness with 3D-FS-SPGR is more accurate.Moreover it can also provide much information adding to 3D construction of cartilage.