Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin administered to pregnant rats during the preimplantation period |
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Authors: | Erminio Giavini Mariangela Prati Claudio Vismara |
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Affiliation: | Institute of Zoology, Laboratory of Embryology and Experimental Morphology, University of Milano, via Celoria 10, 20133 Milano, Italy |
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Abstract: | ![]() 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) was given by gavage to pregnant rats on the 1st–3rd days of gestation in dosages of 0 (control), 0.125, 0.5, and 2 μg/kg/day. The treatment did not increase pre- and postimplantation losses. Mean fetal weight was reduced at the 0.5 and 2 μg/kg dose levels. |
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