河北省承德地区不孕不育症患者弓形虫感染调查

目的 了解承德地区不孕症患者弓形虫感染情况及影响因素. 方法 采用酶联免疫吸附试验（enzyme linked immunosorbent assay,ELISA）对2012年3月至2014年2月在承德市中医院妇产科进行不孕问诊咨询的不孕症患者进行弓形虫抗体检测,同时对不孕患者中的阳性病例进行感染史追溯,用SPSS 13.0软件进行数据统计分析. 结果 1 474例（737对）不孕症患者弓形虫抗体阳性118例,阳性率8.01％;正常对照组349对（698例）,阳性19例,阳性率2.72％,两组差异有统计学意义（x2=22.37,P＜0.01）.不孕症患者中男性阳性74例,阳性率10.04％,女性阳性44例,阳性率5.97％,对照组男性阳性11例,阳性率为3.15％,女性阳性8例,阳性率为2.29％,2组男女比较差异均有统计学意义（P＜0.01）.不孕组118例阳性病例中,35人家庭有养猫养犬历史,占29.66％;54人经常在外就餐,占45.76％; 31人喜吃火锅或烧烤,占26.27％.而在不孕组1 356例阴性病例中仅有97人有养猫养犬历史,占7.15％;132人经常在外就餐,占9.73％;109人喜吃火锅或烧烤,占8.04％. 结论 承德地区不孕症患者弓形虫感染率较高.

Investigation on Toxoplasma infection among patients with infertility in Chengde,Hebei Province

Objective To investigate Toxoplasma infection in patients with infertility and its influencing factors in Chengde,Hebei Province.Methods The Toxoplasma antibody detection by enzyme linked immunosorbent assay （ELISA） was carried out in infertility patients who were consulting in Hospital of Chengde City between March 2012 to February 2014,at the same time,the infection history was traced in the positive cases of infection in patients with infertility.The data were analyzed using SPSS13.0 statistics software.Results 118 cases were Toxoplasma antibody positive in 1 474 cases （737 pairs） of patients with infertility,and positive rate was 8.01％（118/1474） while 19 cases positive in control group with the positive rate of 2.72％ （19/698）,the difference was statistically significant （x2=22.37,P＜0.01）.Seventy four cases were positive in male patients with infertility with the rate of 10.04％（74/737） while 44 cases were positive in female with the rate of 5.97％ （44/737）.In the control group,11 cases were positive in male patients with infertility,the rate was 3.15％（11/349） while 8 cases were positive in female and the rate was 2.29％（8/349）,the difference was statistically significant （P＜0.01）.In 118 positive cases of infertility group,35 cases had a cat or a dog in their family,accounted for 29.66％（35/118）; 54 cases often ate out,accounted for 45.76％（54/118）; 31 cases were fond of eating hot pot or barbecue,accounted for 26.27％（31/118）.In 1 356 negative cases of infertility group,97 cases had a cat or a dog in their family,accounted for 7.15％（97/1 356）; 132 cases often ate out,accounted for 9.73％（132/1 356）; 109 cases were fond of eating hot pot or barbecue,accounted for 8.04％（109/1 356）.Conclusion The Toxoplasma infection rate is higher among infertility patients in Chengde,Hebei Province.