Vascular endothelial growth factor (VEGF) expression is not associated with prognosis in patients with radically resected ampullary carcinoma. |
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Authors: | D Santini B Vincenzi G Perrone C Rabitti D Borzomati S Valeri R Coppola P Magistrelli G Tonini |
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Affiliation: | 1 Department of Medical Oncology, 2 Department of Pathology 3 Department of Surgery, University Campus Bio-Medico, Rome; 4 Department of Surgery, Catholic University of Rome, Italy |
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Abstract: | Vascular endothelial growth factor (VEGF) is known to be a potentangiogenic mitogen that plays an important role in tumor angiogenesis[1]. The correlation between the expression of VEGF and eithermetastasis or a poor prognosis has been reported for severalcancers [2]. Kurahara and colleagues demonstrated that VEGFexpression in patients with pancreatic head cancer is significantlyassociated with lymphatic metastasis and prognosis [3]. |
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