广东阳江辐射高本底地区居民眼晶状体混浊调查

目的 研究长期低剂量电离辐射照射对眼晶状体混浊的影响.方法 在广东省辐射高本底地区和对照地区分别随机整群抽取2个村和3个村的年龄≥45岁的常住居民,进行问卷调查和裂隙灯眼晶状体混浊检查.采用非条件logistic回归分析探讨眼晶状体混浊的危险因素.结果 调整性别、年龄、吸烟、饮酒之后,与对照地区居民相比,辐射高本底地区居民患眼晶状体混浊、皮质性混浊、核性混浊和后囊下混浊的OR值分别为0.99(95%CI:0.72~1.37)、1.45(95%CI:0.99~2.11)、0.82(95%CI:0.60~1.14)、4.05(95%CI:1.56~10.46),提示高本底地区居民眼晶状体后囊下混浊的危险性增高.结论 长期低剂量电离辐射受照可能是眼晶状体后囊下混浊的重要危险因素.

Survey of lens opacities of residents living in high background radiation area in Yangjiang, Guangdong province

Objective To study the effect of long-term low dose ionizing radiation on ocular lens opacities.Methods With random cluster sampling, the residents aged over 45 years were selected from two villages in high background radiation areas(HBRA) in Yangxi County and three control areas in Enping County in Guangdong province, and a questionnaire survey was conducted and slit-lamp eye lens opacity was checked.Results With adjustment of gender, age, smoking and drinking factors compared with the residents living in control areas, the risks of eye lens opacities, cortical opacities, nuclear opacities and posterior subcapsular opacities for residents living in HBRA were 0.99 (95%CI:0.72-1.37), 1.45 (95%CI:0.99-2.11), 0.82 (95%CI:0.60-1.14), and 4.05 (95%CI:1.56-10.46), respectively.Conclusions Long-term low dose ionizing radiation exposure is probably an important risk factor for eye posterior subcapsular lens opacities.