老年2型糖尿病合并非酒精性脂肪肝与下肢动脉疾病的关系

目的探讨老年2型糖尿病（T2DM）合并非酒精性脂肪肝的发生与下肢动脉疾病（LEAD）的关系。方法对89例老年2型糖尿病患者，根据有无合并非酒精性脂肪肝分为合并脂肪肝组和非脂肪肝组。对这些患者进行体格检查、生化检查及下肢动脉彩色多普勒超声检查。结果老年2型糖尿病合并脂肪肝组BMI、WHR、FINS、HOMA—IR、LDL—C、TG较非脂肪肝组升高（P〈0．05）。两组间LEAD发生率无显著性差异，但合并脂肪肝组重度及极重度LEAD发生率较高。结论老年2型糖尿病合并脂肪肝组更易出现血脂异常、胰岛素抵抗及较严重下肢动脉疾病。

The relationship between lower extremity atherosclerotic disease and non-alcoholic fatty liver in aged patients with type 2 diabetes mellitus

Objective To investigate the relationship between lower extremity atherosclerotic disease (LEAD)and non-alcoholic fatty liver(NAFL)in aged patients with type 2 diabetes mellitus(T2DM).Methods According to whether the patients had NAFL,89 cases of aged patients with T2DM were divided into fatty liver group and non-fatty fiver group.The physical examination,biochemical tests and ultrasonic Doppler examinations were conducted in these patients.Results The levels of BMI,WHR,FINS,HOMA-IR,LDL-C and TG increased significantly in fatty liver group compared with non-fatty fiver group(P<0.05).The incidence of LEAD was not different between two groups,but the incidence of more severe LEAD was higher in the group with NAFL.Conclusion NAFL in aged T2DM patients have remarkable dyslipidemia,insulin resistance and severe LEAD.