动脉流量对于肌肉萎缩的影响

本文通过分析动脉流量与肌肉萎缩之间的内在联系,为临床上残肢康复研究提供必要的信息和理论支撑。对单侧截肢患者的残肢与健肢的动脉模型进行三维重建,通过血流动力学数值计算对各动脉出口质量流量进行双侧对比分析;测量双侧大腿肌肉面积,并分析残肢的肌肉萎缩程度。通过血供关系对比分析动脉流量与肌肉萎缩程度之间的关系。结果表明,股直肌、股外侧肌、股内侧肌萎缩较为严重,其滋养血管股浅动脉及旋股外动脉质量流量缩减也较严重;股薄肌、长收肌、股二头肌长头肌肉萎缩程度较轻,而其滋养血管股深动脉及旋股内动脉质量流量缩减也较轻。残肢肌肉的萎缩程度与对应供血动脉的质量流量缩减程度成正相关,两者在康复过程中或存在相互促进的关系。

Effect of arterial flow on muscle atrophy

This study analyzed the inherent relation between arterial blood mass flow and muscle atrophy of residual limb to provide some necessary information and theoretical support for the clinical rehabilitation of lower limb amputees.Three-dimensional arterial model reconstruction was performed on both intact side and residual limb of a unilateral transfemoral amputee who is the subject.Then hemodynamic calculation was carried out to comparatively analyze the mass flow state at each arterial outlet of both lower extremities.The muscle atrophy ratio of residual limb was calculated by measuring the cross-sectional area of bilateral muscles.Based on the blood supply relationship,the correlation between arterial blood flow reduction ratio and muscle atrophy ratio was discussed.The results showed that the mass flow of superficial femoral arteries and lateral circumflex femoral arteries severely reduced.Meanwhile rectus femoris,vastus lateralis and vastus medialis which were fed by these arteries showed great atrophy too.On the contrary,the mass flow of deep femoral arteries and medial femoral circumflex arteries slightly reduced.Meanwhile gracilis,adductor longus,long head of biceps which were fed by these arteries showed mild atrophy too.These results indicated that there might be a positive and promotion correlation between the muscle atrophy ratio and the blood mass flow reduction ratio of residual limb during rehabilitation.