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短暂性脑缺血发作与脂蛋白(a)及纤维蛋白原的关系探讨
引用本文:欧利民,郑璇,庄伟端,肖颖秀. 短暂性脑缺血发作与脂蛋白(a)及纤维蛋白原的关系探讨[J]. 实用心脑肺血管病杂志, 2004, 12(1): 18-19
作者姓名:欧利民  郑璇  庄伟端  肖颖秀
作者单位:515041,广东汕头大学医学院第一附属医院神经内科
摘    要:
目的 探讨短暂性脑缺血发作 (Transientischemicattack ,TIA)时脂蛋白 (a) [Lipoprotein(a) ,LP(a) ]及纤维蛋白原 (Fg)的关系。 方法 对 4 8例TIA患者测定血清LP(a)和血浆Fg水平 ,并与 2 5例健康正常人对照。 结果 同对照组比较 ,TIA组患者Lp(a)和Fg水平明显高于对照组 (P <0 0 5 ) ;Lp(a)与Fg水平呈正相关 (P <0 0 1) ,TIA伴有梗塞灶者LP(a)和Fg的水平均高于无梗塞灶者 (P <0 0 5 )。 结论 Lp(a)和Fg水平升高可能是TIA发生发展主要因素之一

关 键 词:短暂性脑缺血发作 脂蛋白(a) 纤维蛋白原 发病机制 血脂 动脉粥样硬化 血栓形成
修稿时间:2003-07-21

A study on the relationships between transient ischemic attack and the change of Lipoprotein (a) and Fibrinogen in blood serum
Ou Limin,Zheng Xuan,Zhuang Weiduan,et al. A study on the relationships between transient ischemic attack and the change of Lipoprotein (a) and Fibrinogen in blood serum[J]. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease, 2004, 12(1): 18-19
Authors:Ou Limin  Zheng Xuan  Zhuang Weiduan  et al
Affiliation:Ou Limin,Zheng Xuan,Zhuang Weiduan,et al Department of Neurology of the First Affiliated Hospital Shantou University Medical College,Shantou,515041,China
Abstract:
Objective To investigate the relationships between transient ischemic attack(TIA) and the change of serum Lipoprotein(a) and plasma Fibrinogen(Fg) Methods The levels of Lp(a) and Fg were measured in 48 patients with TIA 25 healthy people were set as control group Results The levels of Lp(a) and Fg in patients with TIA were higher than control group(P<0 05) In TIA group,the levels of Lp(a) and Fg in those patients with infarction significantly increased compared with those without infarction(P<0 05) Conclusion These results suggest that increased Lp(a) and Fg may play roles in the formation of TIA
Keywords:Transient ischemic attack Lipoprotein(a) Fibrinogen
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