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全反式维甲酸治疗急性早幼粒细胞白血病14例临床分析
引用本文:张吉仙,程定珍,张缙鸾,温丙昭,哈力代,付美兰. 全反式维甲酸治疗急性早幼粒细胞白血病14例临床分析[J]. 新疆医科大学学报, 1993, 0(1)
作者姓名:张吉仙  程定珍  张缙鸾  温丙昭  哈力代  付美兰
作者单位:新疆医学院第一附属医院血液科,新疆医学院第一附属医院血液科,新疆医学院第一附属医院血液科,新疆医学院第一附属医院血液科,新疆医学院第一附属医院血液科,新疆医学院第一附属医院血液科
摘    要:
应用国产全反式维甲酸(RA)治疗急性早幼粒细胞白血病(APL)14例。结果单用RA治疗,6例完全缓解(CR)率为83.3%,RA合并化疗8例CR率为87.5%,两组总的CR率为85.7%。在治疗中白细胞数明显升高,出血倾向减轻。

关 键 词:全反式维甲酸  诱导分化  急性早幼粒细胞白血病

A Clinical Study of 14 Patients with APL Treated with All-trans Retinoic Acid
Zhang Jixian. et al. A Clinical Study of 14 Patients with APL Treated with All-trans Retinoic Acid[J]. Journal of Xinjiang Medical University, 1993, 0(1)
Authors:Zhang Jixian. et al
Affiliation:Zhang Jixian. et al Department of Hemotology,First Affiliated Hospital,Xinjiang Medical College
Abstract:
Fourteen cases with APL were treated with all-trans retinoic acid(RA). The result showed that in 6 cases with RA alone, CR was 83. 3%,and 8 cases, treated with RA combinated with chemotherapy, CR 87. 5%. A total CR was 85. 7% in two groups. No significant side effects wore found during treatment.
Keywords:all-trans retinoic acid  induced differentiation  acute promyelocytic leukemia (APL)
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