| 直肠非甾体类抗炎药对ERCP术后胰腺炎的预防作用 |
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| 引用本文： | 夏挺松,刘鹏飞. 直肠非甾体类抗炎药对ERCP术后胰腺炎的预防作用[J]. 中华消化内镜杂志, 2010, 27(1): 301-302. DOI: 10.3760/cma.j.issn.1007-5232.2010.06.008 |
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| 作者姓名： | 夏挺松 刘鹏飞 |
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| 作者单位： | 江苏省江阴市人民医院消化科,214400; |
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| 摘 要： | Objective To investigate the preventive and therapeutic effects of nonsteroidal anti-inflammatory drugs ( NSAIDs) via rectum for hyperamylasemia and pancreatitis after ERCP (endoscopic retrograde cholangiopancreatography).Methods Sixty patients who underwent ERCP for various reasons were randomly divided into preventive and control groups.In addition to routine diazepam (10 mg) and anisodamine (10 mg) given intramuscularly in both groups before ERCP, 100 mg of indometacin suppositories was administered by rectum in preventive group.Serum amylase level was measured before and 6 hours and 24 hours after the procedure.Results Serum amylase levels at 6 hours after ERCP in preventive and control groups were (367.5 ± 268.7 ) U/L and (1034.2 ± 713.5 ) U/L, respectively ( P < 0.05 ), which were (324.9±142.3)U/L and (826.8 ±395.7)U/L, respectively, at 24 hours after ERCP (P<0.05).Conclusion Rectal use of NSAIDs can prevent hyperamylasemia and acute pancreatitis induced by ERCP.
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| 关 键 词： | 胰腺炎 直肠 内窥镜逆行胰胆管造影术 非甾体类抗炎药 |
Preventive effect of rectal nonsteroidal anti-inflammatory drugs for post-ERCP pancreatitis |
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| XIA Ting-song,LIU Peng-fei. Preventive effect of rectal nonsteroidal anti-inflammatory drugs for post-ERCP pancreatitis[J]. Chinese Journal of Digestive Endoscopy, 2010, 27(1): 301-302. DOI: 10.3760/cma.j.issn.1007-5232.2010.06.008 |
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| Authors: | XIA Ting-song LIU Peng-fei |
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| Abstract: | |
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| Keywords: | PancreatitisRectumEndoscopic retrograde cholangiopancreatographyNSAIDs |
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