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| 病理性瘢痕中丙二醛含量的测定 | |
| 引用本文： | 李伟人,岑瑛,陈波. 病理性瘢痕中丙二醛含量的测定[J]. 华西医学, 2006, 21(1): 28-28 |
| 作者姓名： | 李伟人 岑瑛 陈波 |
| 作者单位： | 1. 四川大学华西医院,烧伤整形科,四川成都,610041 2. 四川大学华西医院,普外科,四川成都,610041 |
| 摘 要： | 目的:了解病理性瘢痕中脂质过氧化水平的变化。方法:应用化学比色法测定正常人皮肤(8例)、增生性瘢痕(10例)、瘢痕疙瘩(10例)及成熟瘢痕(7例)组织中丙二醛的含量。结果:与正常人皮肤比较,增生性瘢痕和瘢痕疙瘩中丙二醛含量明显升高(P<0·05),成熟瘢痕与正常人皮肤比较无差异(P>0·05);与成熟瘢痕比较,增生性瘢痕和瘢痕疙瘩中MDA含量非常显著升高(P<0·01);增生性瘢痕和瘢痕疙瘩比较无差异(P>0·05)。结论:病理性瘢痕中自由基含量增加引起脂质过氧化程度加重,瘢痕过度增生可能与此有关。 |
| 关 键 词： | 增生性瘢痕 瘢痕疙瘩 丙二醛 |
| 文章编号： | 1002-0179(2006)01-0028-01 |
| 收稿时间： | 2005-09-10 |
| 修稿时间： | 2005-09-10 |
Determination of the Contents of Malondialdehyde in Pathological Scar Tissues |
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| LI Wei-ren,CEN Ying,CHEN Bo. Determination of the Contents of Malondialdehyde in Pathological Scar Tissues[J]. West China Medical Journal, 2006, 21(1): 28-28 | |
| Authors: | LI Wei-ren CEN Ying CHEN Bo |
| Affiliation: | West China Hospital, Sichuan University, Chengdu 610041, China |
| Abstract: | Objective:To investigate the change of lipoperoxidation in pathological scar tissues.Methods:The content of malondialdehyde was detected by spectrophotometric method in the following tiscues:hpertrophic scar(10 cases)?keloid(10 cases) and mature scar(7 cases)and normal skin(8 cases),which was used as control.Results:The contents of malondialdehyde in hypertrophic scar and keloid were increased significantly in comparison with the normal skin and mature scar(P<0.05).The difference between the mature scar and normal skin was not significant(P>0.05).Conclusion:The level of lipoperoxidation was eleuated because of the accumulation of free radicals in pathological scar tissues,which probably causes hyperplasia of scar tissues. |
| Keywords: | Hypertrophic scar keloid malondialdehyde |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |