TCT联合阴道镜检查提高宫颈疾病检出率

【目的】探讨液基薄层细胞学（TCT）联合阴道镜检查对宫颈病变的诊断价值。【方法】选择妇科门诊临床可疑患者610例进行宫颈病变筛查，其中338例行TCT联合阴道镜活检（实验组），272例直接阴道镜检查并镜下取材活组织检查（对照组）。最终以病理组织诊断为标准，比较两组组织学诊断阳性率。【结果】TCT联合阴道镜检查与病理组织阳性符合率为71．30％（241／338），直接阴道镜下取材活检阳性率为31．25％（85／272）。【结论】TCT联合阴道镜下活组织病理检查可提高宫颈病变诊断率，是筛查和诊断宫颈病变的可靠手段。

TCT combined with colposcope examination improved the detection rate of cervix diseases

[Objective] To investigate the diagnostic value of thinprep cytologic test (TCT) combined with biopsy under colposcope for the diagnosis of cervical intraepithelial neoplasid (CIN) . [Methods] A total of 610 suspicious patients were assigned to receive TCT combined with biopsy under colposcopy (TCT group, 338 patients) or biopsy under col-poseopy ramdomly (control group, 272 patients) . Pathologic examination of biopsy sample was used as gold standard. [Results] The coincidence on diagnosis of cervical lesions between TCT group and pathologic examination of biopsy sam-ple was 71.3% (241/338), the coincidence on diagnosis of cervical lesions between control gronp and pathologic exami-nation of biopsy sample was 31.25% (55/272), the difference was signifient (P < 0.01) . [Conclusions] TCT com-bined with biopsy under colposcopy may be a reliable method to screen and diagnose the precancerosis of cervix.