HPLC法测定心可宁滴丸中丹酚酸B的含量 |
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引用本文: | 袁旭江,沈嘉茵,朱盛山.HPLC法测定心可宁滴丸中丹酚酸B的含量[J].亚太传统医药,2008,4(3):37-39. |
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作者姓名: | 袁旭江 沈嘉茵 朱盛山 |
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作者单位: | 广东药学院,广东广州,510006 |
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基金项目: | 广东省中医药管理局科研项目,国家自然科学基金 |
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摘 要: | 目的:对中药复方制剂心可宁滴丸中的丹酚酸B进行含量测定。方法:采用高效液相色谱法,以乙腈-0.1%磷酸水液(21.5:78.5)为流动相;检测波长为286nm。结果:丹酚酸B在0.196~1.960μg范围内均与色谱峰面积呈良好的线性关系,r为0.99996,平均加样回收率为97.83%(N=5),RSD=3.33%。结论:本方法快速简便,灵敏度和稳定性高,为心可宁滴丸的质量标准奠定了良好的基础。
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关 键 词: | 高效液相色谱 心可宁滴丸 丹酚酸B |
Determination of Salvianolic Acid B in XinKening Drop Pills by HPLC |
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Abstract: | Objective: To establish a method to determine salvianolic acid B in xinkening drop pills. Methods: The Rp-HPLC method was applied with Acetonitrile and 0. 1% H3PO4 water as mobile phase(21. 5178. 5), with detection wavelength at 286nm. Results: In the range from 0. 196 to 1. 960μg, salvianolic acid B was in a good line with chromatograph peaks area,r=0. 9996, the average recovery ratio is 97. 830% (N= 5) ,RSD= 3.33 %. Conclusions: The method is quickly simple with a high intelligent degree and stabilities. The method could be used to control quality effectively as a good base. |
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Keywords: | HPLC XinKening Drop Pills Salvianolic acid B |
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