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| 糖尿病性心脏病研究进展 | |
| 引用本文： | 邱俊霖,罗说明,周智广. 糖尿病性心脏病研究进展[J]. 中国动脉硬化杂志, 2020, 28(8): 679-687 |
| 作者姓名： | 邱俊霖 罗说明 周智广 |
| 作者单位： | 中南大学湘雅二医院代谢内分泌科 糖尿病免疫学教育部重点实验室 国家代谢性疾病临床医学研究中心,湖南省长沙市 410011 |
| 基金项目： | 国家重点研发计划(2016YFC1305000,2016YFC1305002)；湖南省自然科学基金面上项目(2018JJ2573)；湖南省科技重大专项(2017SK1020) |
| 摘 要： | 近年糖尿病发病率急剧增高,成为仅次于心脑血管疾病和癌症的又一大疾病,严重危害人类健康。而在糖尿病当中,糖尿病性心脏病最严重,致死率极高。糖尿病可通过3种方式影响心脏:冠心病、糖尿病心肌病和心脏自主神经病变。不同糖尿病类型,发病情况不同。3种糖尿病性心脏病的发病机制有共同的地方,但在筛查及治疗的手段上又有所不同。本文整合相关的最新进展旨在分析阐明糖尿病性心脏病的机制、临床筛查和潜在治疗途径。 |
| 关 键 词： | 糖尿病性心脏病 冠心病 糖尿病心肌病 心脏自主神经病变 1型糖尿病 2型糖尿病 |
| 收稿时间： | 2020-05-18 |
| 修稿时间： | 2020-05-25 |
Research progress of diabetic heart disease |
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| QIU Junlin,LUO Shuoming,ZHOU Zhiguang. Research progress of diabetic heart disease[J]. Chinese Journal of Arteriosclerosis, 2020, 28(8): 679-687 | |
| Authors: | QIU Junlin LUO Shuoming ZHOU Zhiguang |
| Affiliation: | Department of Metabolism and Endocrinology & Key Laboratory of Diabetes Immunology, Ministry of Education & National Clinical Research Center for Metabolic Diseases, the Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China |
| Abstract: | The incidence rate of diabetes has increased dramatically in recent years, becoming another major disease next to cardiovascular and cerebrovascular diseases and cancer, and seriously endangering human health. Diabetic heart disease is the most serious in diabetes, with extremely high mortality. Diabetes affects the heart in three ways:coronary artery disease, diabetic cardiomyopathy, and cardiac autonomic neuropathy. Different types of diabetes have different incidence. The pathogenesis of the three types of diabetic heart disease has something in common, but the means of screening and treatment are different. This review integrates the latest developments related to the mechanism, clinical screening and potential therapeutic approaches of diabetic heart disease. |
| Keywords: | diabetic heart disease coronary artery disease diabetic cardiomyopathy cardiac autonomic neuropathy type 1 diabetes mellitus type 2 diabetes mellitus |
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