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立体定向放射治疗脊柱转移瘤疗效分析
引用本文:陈永顺,单国用,庆明轩,张大勇,张现军. 立体定向放射治疗脊柱转移瘤疗效分析[J]. 肿瘤基础与临床, 2005, 18(5): 333-334
作者姓名:陈永顺  单国用  庆明轩  张大勇  张现军
作者单位:郑州市第五人民医院放疗科,河南,郑州,450003;郑州市第五人民医院放疗科,河南,郑州,450003;郑州市第五人民医院放疗科,河南,郑州,450003;郑州市第五人民医院放疗科,河南,郑州,450003;郑州市第五人民医院放疗科,河南,郑州,450003
摘    要:目的观察立体定向放射治疗脊柱转移瘤的疗效与不良反应。方法应用全身伽玛刀治疗脊柱转移瘤24例,肿瘤组织照射剂量38.2~46.8 Gy,10~13分次,13~17天完成。结果放疗后疼痛完全缓解(CR)7例,部分缓解(PR)12例,轻微疗效(MR)2例,止痛有效率90.5%。骨转移灶完全消失3例,明显缩小13例,治疗后生活质量评分较治疗前明显改善,消化道反应和骨髓抑制等不良反应轻微。结论立体定向放射治疗脊柱转移瘤止痛效果迅速持久,能明显改善患者的生活质量,控制肿瘤效果满意,值得推广。

关 键 词:立体定向放射治疗  脊柱转移瘤  疗效
文章编号:1003-1464(2005)05-0333-02
修稿时间:2005-02-28

Analysis on Stereotactic Radiotherapy for Spinal Metastases
Chen Yongshun,Shan Guoyong,Qing Mingxuan,Zhang Dayong,Zhang Xianjun. Analysis on Stereotactic Radiotherapy for Spinal Metastases[J]. Journal of Basic and Clinical Oncology, 2005, 18(5): 333-334
Authors:Chen Yongshun  Shan Guoyong  Qing Mingxuan  Zhang Dayong  Zhang Xianjun
Abstract:Objective To evaluate the curative effect and side-effect of stereotactic radiotherapy for spinal metastases.Methods 24 patients with spinal metastases were received stereotactic radiotherapy. The method of radiotherapy was 2.8-3.6 Gy per fraction ,with a total dose of 38.2-(46.8 Gy) in 10-13 times over 13-17 days.Results The total remission rate of pain was 90.5%(19/21), all the patients were improved in the quality of life and no evident side-effect was showed.Conclusions Stereotactic radiotherapy should be considered as an effective approach in the treatment of spinal metastases.
Keywords:stereotactic radiotherapy  spinal metastases  curative effect
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