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参芪合剂对小鼠胃排空和肠推进的作用
引用本文:李伟,郑天珍,蔺美玲,瞿颂义,丁永辉,卫玉玲.参芪合剂对小鼠胃排空和肠推进的作用[J].中国中医基础医学杂志,2006,12(7):517-518.
作者姓名:李伟  郑天珍  蔺美玲  瞿颂义  丁永辉  卫玉玲
作者单位:1. 兰州大学基础医学院,生理教研室,甘肃,兰州,730000;甘肃省新药临床前研究重点实验室,甘肃,兰州,730000
2. 甘肃省食品药品监督管理局,甘肃,兰州,730000
3. 甘肃省药检所,甘肃,兰州,730000
摘    要:用不同浓度参芪合剂灌胃后,观察营养半固体糊的胃内残留率和用碳末法计算小肠的推进百分比。观察参芪合剂对在体小鼠胃排空及肠推进作用的影响并初步探讨其作用机制。结果发现,参芪合剂(40g/kg)抑制小鼠胃排空,但对阿托品所致胃排空延缓有拮抗作用。参芪合剂(30g/kg,40g/kg)促进小肠推进作用,对阿托品和去甲肾上腺素所致的肠推进抑制有拮抗作用。

关 键 词:参芪合剂  胃排空  肠推进  阿托品  去甲肾上腺素
文章编号:1006-3250(2006)07-0517-02
收稿时间:2005-04-03
修稿时间:2005年4月3日

Effect of Shenqi Mixture on Gastric Emptying and Intestinal Propelling in Mice
LI Wei,ZHENG Tian-zhen,LIN Mei-ling,QU Song-yi,DING Yong-hui,WEI Yu-ling.Effect of Shenqi Mixture on Gastric Emptying and Intestinal Propelling in Mice[J].Chinese Journal of Basic Medicine In Traditional Chinese Medicine,2006,12(7):517-518.
Authors:LI Wei  ZHENG Tian-zhen  LIN Mei-ling  QU Song-yi  DING Yong-hui  WEI Yu-ling
Abstract:The effect mixture decoction of Dangshen and Hangqi(shenqi decoction) on gastric emptying and small intestinal propulsion were studied in mice.The shenqi decoction(40g/kg) inhibited the gastric emptying and significantly antagonized the delayed gastric emptying induced by atropine.The shenqi decoction(30g/kg,40g/kg) promoted small intestinal propulsion and significantly antagonized the inhibition of small intestinal propulsion induced by atropine and norepinephrine.
Keywords:Shenqi decoction  Gastric emptying  Small intestinal propulsion  Atropine  Norepinephrine(NE)
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