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The Application of Beta-Tricalcium Phosphate in Implant Dentistry: A Systematic Evaluation of Clinical Studies
Authors:Elisabet Roca-Millan,Enric Jané  -Salas,Antonio Marí  -Roig,Á  lvaro Jimé  nez-Guerra,Ivá  n Ortiz-Garcí  a,Eugenio Velasco-Ortega,José    pez-Ló  pez,Loreto Monsalve-Guil
Affiliation:1.Department of Odontostomatology, School of Dentistry, Faculty of Medicine and Health Sciences, University of Barcelona, 08907 Barcelona, Spain; (E.R.-M.); (E.J.-S.);2.Department of Clinical Sciences, Faculty of Medicine and Health Sciences, University of Barcelona, 08907 Barcelona, Spain;3.Department of Odontostomatology, Faculty of Dentistry, University of Seville, 41013 Seville, Spain; (Á.J.-G.); (I.O.-G.); (E.V.-O.); (L.M.-G.)
Abstract:The demand for synthetic graft materials in implant dentistry is rising. This systematic review aims to evaluate the survival rate of dental implants placed simultaneously with bone regeneration procedures using the material β-tricalcium phosphate, one of the most promising synthetic graft materials. The electronic search was conducted in PubMed, Scielo, and the Cochrane Central Register of Controlled Trials. Five randomized clinical trials, one non-randomized controlled clinical trial and four observational studies without control group were include. Implant survival rate and other clinical, radiographic, and histological parameters did not differ from those of implants placed simultaneously with another type of graft material, or placed in blood clots or natural alveolar ridges. Based on the available literature, β-tricalcium phosphate seems to be a promising graft material in implant dentistry. Nevertheless, more randomized clinical trials, with long follow-up periods, preoperative and postoperative CBCT, and histological analysis, are necessary to assess its long-term behavior.
Keywords:beta-tricalcium phosphate   biomaterials   bone substitutes   dental implants   oral implantology
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