| DCF方案治疗老年晚期胃癌的临床观察 |
| |
| 引用本文： | 汪志求,韩光锋,段爱雄. DCF方案治疗老年晚期胃癌的临床观察[J]. 安徽卫生职业技术学院学报, 2011, 10(6): 19-20,22 |
| |
| 作者姓名： | 汪志求 韩光锋 段爱雄 |
| |
| 作者单位： | 安庆市立医院 安徽246001 |
| |
| 摘 要： | 目的:观察多西他赛联合顺铂、5-氟尿嘧啶治疗老年晚期胃癌的疗效和毒副反应。方法:分析老年晚期胃癌31例,多西他赛75mg/m2,静脉滴注,d1;顺铂20mg/m2静脉滴注,d1~5;5-FU500 mg/m224小时持续泵入,d1~5。21天为一个周期,2个周期后评价疗效。结果:全组31例患者CR1例,PR14例,有效率(CR+PR)48.4%(15/31),中位进展时间为4.3个月,主要不良反应为白细胞下降。结论:DCF方案治疗老年晚期胃癌疗效较好,且毒副反应可以耐受。
|
| 关 键 词： | 多西他赛 氟尿嘧啶 胃癌 |
Clinical observation of DCF in the treatment of patients with advanced gastric cancer |
| |
| WANG Zhi-qiu,HAN Guang-feng,DUAN Ai-xiong. Clinical observation of DCF in the treatment of patients with advanced gastric cancer[J]. Journal of Anhui Heaith Vocational & Technical College, 2011, 10(6): 19-20,22 |
| |
| Authors: | WANG Zhi-qiu HAN Guang-feng DUAN Ai-xiong |
| |
| Affiliation: | Anqing Municipal Hospital, Anqing 246001, Anhui WANG Zhi-qiu, HAN Guang-feng, DUAN Ai-xiong |
| |
| Abstract: | Objective： To observe the efficacy and toxicity of combination of docetaxel,5-fluorouracil,cis- platin in the treatment of patients with advanced older gastric cancer. Methods： Thirty-one older patients with advanced gastric cancer were received docetaxel（75mg/m2 dl）,cisplatin（20mg/m2 dl-d5）, 5-fluorouracil（500mg/m2 continous ivgtt,24h,d1-d5）.The treatment was repeated every 3 weeks.The evaluation of the efficacy and adverse effects was carried out after two cyclics. Results ：In the 31 cases ,there was 1 case of CR and 14 cases of PR.The overall response rate was 48.4%（1531）.The median time to progression was 4.3 months , The main toxicities was leucopenia. Conclusion： The combined regimen of DCF is effective and can be tolerated by older patients with advanced astrle cancer_ |
| |
| Keywords: | Docetaxel 5-fluorouracil gastric cancer |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
