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Differences in localization of substantia nigra vs interaural line in Wistar and Sprague Dawley rats
Authors:Torben Skarsfeldt
Affiliation:Department of Pharmacology and Toxicology, H. Lundbeck & Co. A/S, Ottiliavej 7ndash;9, DK-2500 Valby-Copenhagen, Denmark
Abstract:
The position of substantia nigra anterior to the interaural line has been correlated with body weight in Wistar rats. A regression line y=0.0050x+1.36 makes it possible to locate the substantia nigra in different sized rats ranging between 140 g and 460 g. This equation is not valid for Sprague Dawley rats. The position of bregma anterior to the interaural line has also been examined. A fairly good correlation was found for Sprague Dawley rats while the position of bregma in Wistar rats was much more variable.
Keywords:Substantia nigra  Stereotaxic localization  Interaural line  Rats  Bregma
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