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Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy |
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| Authors: | Press Joshua Z Kenyon Jennifer A Xue Hui Miller Melinda A De Luca Alessandro Miller Dianne M Huntsman David G Gilks C Blake McAlpine Jessica N Wang Y Z |
| Affiliation: | aDepartment of Obstetrics and Gynaecology, University of British Columbia, Vancouver, B.C., Canada V6H 3V5;bDepartment of Pathology, Genetic Pathology Evaluation Centre, Vancouver General Hospital, Centre for Translation and Applied Genomics, BC Cancer Agency and University of British Columbia, Vancouver, BC, Canada V5Z 4E6;cDepartment of Cancer Endocrinology, BC Cancer Agency, Vancouver, BC, Canada V5Z 4E6 |
| Abstract: | |
| Keywords: | Ovarian carcinoma Xenograft mouse model BRCA genes Chemotherapy PARP inhibitor |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |