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肝癌瘤苗激活的TIL对K562细胞杀伤活性的研究
引用本文:刘剑勇 张丽生. 肝癌瘤苗激活的TIL对K562细胞杀伤活性的研究[J]. 广西医学, 1998, 20(5): 749-751
作者姓名:刘剑勇 张丽生
作者单位:广西医科大学附属肿瘤医院普瘤科,广西肿瘤防治研究所
摘    要:
目的:为也提高TIL的抗肿瘤细胞活性。方法;使用冷冻方法制成肝癌瘤苗。用于激活TIL,观察基杀伤K562细胞活性的改变。结果:经瘤苗激活的TIL在培养扩增10天,20天,30天和40天对K562细胞的杀伤率均有明显提高,其中以培养扩增30天时为最高。

关 键 词:肝癌瘤苗 激活 TIL K562细胞 抗瘤活性

Study on the killing K 562 cell activity of TIL stimulated by liver cancer vaccines
Liu Jianyong,Li Ting,Yang Nanwu,et al. Study on the killing K 562 cell activity of TIL stimulated by liver cancer vaccines[J]. Guangxi Medical Journal, 1998, 20(5): 749-751
Authors:Liu Jianyong  Li Ting  Yang Nanwu  et al
Affiliation:Nanning 530021
Abstract:
Objective: To enhance the anti-tumor activity of TIL Method: The liver cancer vaccines were made by cryodestorying method The TIL was stimulated by liver cancer vaccines and its anti-tumor activity was observed Result: The injurious rates of TIL stimulated by liver cancer vaccines and after cultured for 10 days, 20 days, 30 days and 40 days for K 562 cells were increased obviously Among them, the stimulated TIL after cultured for 30 days showed the highest killing K 562 cell activity Conlusion: The results indicated that the TIL stimulated by liver cancer vaccines possessed higher casualty function for K 562 Cells
Keywords:Liver cancer vaccines  Stimulation  TIL  K 562 cell  Anti-tumor activity
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