| Abstract: | ![]()
The effect of the gallate of the alkaloid cynoglossophine-heliosupine (cyngal), isolated from the plantCynoglossumofficinale L., of the Boraginaceae family, on gastric secretion was studied in rats. Cyngal was shown to stimulate gastric secretion in rats starting from a dose of 0.25 mg/kg. This action is explained by the ability of the alkaloid to liberate histamine from labile depots.Department of Pharmacology, Leningrad Pharmaceutical Chemical Institute. Laboratory of Experimental Pharmacology, Research Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad. (Presented by Academician of the Academy of Medical Sciences of the USSR S. V. Anichkov.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 84, No. 12, pp. 679–682, December, 1977. |
