成都地区各年龄段女性群体人乳头瘤病毒感染统计学分析

目的了解成都地区人乳头瘤病毒感染的年龄分布情况,以及高危亚型与低危亚型感染和单重感染与多重感染分别与临床症状的相关性。方法收集2011年3-12月来院做人乳头瘤病毒检查的病人标本500份,运用反向点杂交方法对其进行分型检测,结果通过excel2003和SPSS 13.0软件包进行统计分析。结果 500例标本中258例人乳头瘤病毒呈阳性,感染率为51.6%,低危阳性与高危阳性分别130例和128例,但不同临床症状低危感染与高危感染分布有很大差异,总的来说随着临床症状严重性增加高危阳性感染率增加,发生多重感染的概率增大。结论通过统计不同年龄段的感染情况,发现16～30岁是女性感染人乳头瘤病毒的高峰期,人乳头瘤病毒感染有年轻化趋势,但中老年女性群体中人乳头瘤病毒感染率依然居高不下。

Statistic Analysis of Human Papilloma Virus Infection of Different Age Group of Women in Chengdu Region

Objective To understand the age distribution of human papilloma virus infection and the association between high-risk subtype or multiple infection and clinical symptoms. Methods 500 patient specimens from March 2011 to December 2011 were collected and genotyped with reverse dot blot method, the results were analyzed by excel 2003 and spss13.0 package. Results Among 500 specimens,258 cases were positive with human papilloma virus（HPV）,the infection rate was 51. 6~,low-risk and high-risk positive was 130 cases and 128 cases respectively. However, among different clinical symptoms the distribution of low-risk and high-risk were very different. In general, high-risk infection rate increased with the severity of clinical symptoms. Similarly, with the increase of severity of clinical symptoms, the probability of multiple infection increased. Conclusion Through the statistic of infection of different ages,we found that 16-30 was the peak period of human papilloma virus infection, but the human papilloma virus infection rate in middle-aged and older female group was still high.